Adi Millman's research involved a fascinating investigation of bacterial defense mechanisms against bacteriophages (viruses that infect bacteria). We plan to transfer the research in a microgravity environment, such as that experienced during parabolic flight maneuvers.
Objective: The experiment explores how microgravity influences the interaction between bacteria and bacteriophages, focusing on bacterial defense mechanisms.
Implications: This research holds significance for understanding how bacterial communities might behave in space environments, such as aboard space stations or during long-duration interplanetary missions. Understanding these interactions could inform the development of better antibacterial strategies and enhance our knowledge of microbial life in space.
Overall, this experiment not only advances our understanding of bacteria-phage interactions but also contributes to the broader field of astrobiology and microbial ecology in space habitats.
Bacterial Retrons Function In Anti-Phage Defense
Methodology:
Parabolic Flights: The experiment will be conducted using parabolic flights, which create short periods of microgravity. During these flights, an aircraft follows a parabolic trajectory, providing around 20-30 seconds of reduced gravity at the peak of each parabola.
Sample Preparation: Bacterial cultures and corresponding bacteriophages will be carefully prepared and sealed in specialized containers to prevent any contamination and allow for controlled interactions during the flight.
Experimental Design: An OTS small incubator with pre-prepared samples will be mounted inside a glove box with a power outlet hole in the outer box.
Data Collection and Analysis: During the microgravity phase, a go-pro will monitor the movement of the dishes. Key metrics that will be monitored include the rate of bacterial infection by phages and the effectiveness of bacterial defense mechanisms. These would be monitored post-flight.
Initial Design of the Experiment
About Me
I am a dedicated professional with a strong academic foundation. I earned an MBA in Biomedical Management and a B.Sc. in Biology from Tel Aviv University, where I was honored with several accolades.
My career in strategic product leadership spans diverse sectors, including medical devices, SaaS, and healthcare. My previous roles at 3D Systems and Anthem Inc. were marked by significant achievements in driving innovation, reducing costs, and expanding product reach.
Outside my professional endeavors, I am passionate about community engagement and actively participate in mentoring programs and initiatives for women's career advancement. I enjoy traveling and exploring my interests in aerial acrobatics and Acro yoga.
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